Mexican Chicken Casserole

Mexican Chicken Casserole is an easy baked chicken recipe for those busy days. Chicken is flavored with taco seasoning, smothered with salsa and cheddar cheese and baked to perfection, making this salsa chicken a favorite weeknight recipe!

Mexican Chicken Casserole

Need to get a fabulously delicious dinner on the table in a hurry with just a few ingredients? Salsa Chicken is your answer! Taco seasoned chicken breasts, surrounded with salsa and cheese, bake in the oven creating juicy chicken with a flavorful topping! 

Add a sprinkle of chopped cilantro and your family won't be able to get enough of this chicken salsa recipe! They'll be requesting our salsa chicken recipe over and over again!

Oh, and may I make a suggestion?

Salsa chicken and rice make a great combo and our Fiesta Saffron Rice is the perfect accompaniment when it's a Mexican salsa chicken dinner night at your house!

Chicken in salsa tastes amazing with just chopped cilantro sprinkled on top but feel free to add your favorite toppings, such as a dollop of sour cream, a sprinkling of sliced scallions and a drizzle of fresh lime juice!

Trust me when I say, you are going to absolutely love this chicken in salsa recipe because not only does it taste delicious but it is so easy to make with just five ingredients!

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How to make a Mexican Chicken Casserole

Scroll down for the full recipe instructions and ingredient amounts in the recipe card below

1. Preheat oven to 375F.
2. Coat a 2-quart baking dish with non-stick cooking spray.
3. Season both sides of chicken with taco seasoning mix. Arrange in prepared baking dish. Top with salsa.
4. Bake 25 minutes.
5. Top with shredded cheese. Bake until chicken is cooked through and cheese is melted, 5 minutes. Meat thermometer should read 165F.
6. Sprinkle with chopped cilantro.

What to serve with salsa chicken

• Jalapeno Cheddar Cornbread
• Fresh Tomato Salsa
• Mexican Street Corn Salad

Swirls of Flavor Recipe Tips

• Top with your favorite toppings, such as sour cream and scallions
• Serve with lime wedges
• Add some heat and top with pickled jalapenos
• Add crumbled queso fresco, always referred to as queso blanco, over the cheddar cheese layer before baking

Substitutions

• Substitute salsa verde for the salsa
• Make this recipe with shredded taco cheese instead of the shredded cheddar cheese
• Substitute boneless skinless chicken thighs for the boneless chicken breasts
• You can use pico de gallo in place of the salsa

Ingredients for chicken with salsa recipe

• boneless skinless chicken breasts
• taco seasoning
• salsa
• cheddar cheese
• cilantro

Easy Chicken Recipes

Looking for more easy and delicious chicken recipes? Here you go!

• Indian Butter Chicken combines warm spices with the simple ingredients of onion, butter, tomato and garlic creating tender chicken in a creamy tomato sauce. An easy chicken dinner that makes an impressive meal for entertaining too!
• Fire up the grill for Chili Spiced Chicken topped with a cilantro lime scented gremolata and finished with a drizzle of fresh lime juice.

• Thai Chicken Lettuce Wraps combine ground chicken with fresh ginger, garlic and Thai basil for a burst of Thailand flavor! A quick cook on the stove top, spoon into lettuce leaves and drizzle with fresh lime juice and your taste buds will thank you!
• If you love a refreshing margarita cocktail then you'll definitely want to serve up Strawberry Basil Margarita Chicken brimming with the sweet juiciness of strawberries, fragrant aroma of fresh basil and the lime flavor of the must-have summertime Margarita cocktail.

• If you're looking for a classic Italian chicken recipe then Chicken Picatta is it! Tender thin chicken breasts in a light lemon sauce with tangy capers, Chicken Piccata is a classic dish that every cook needs to have in their recipe line up! 
• Slow Cooker Moroccan Chicken will transport you to a far away place with it's sweet and tangy raisins and olives and combination of spices.

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5 from 3 votes

Mexican Chicken Casserole

Mexican Chicken Casserole is an easy baked chicken recipe for those busy days. Juicy chicken breasts flavored with taco seasoning are smothered with salsa and cheddar cheese and baked to perfection, making this salsa chicken a soon-to-be favorite weeknight recipe!

Course Main Course

Cuisine Mexican

Keyword baked salsa chicken, Mexican chicken casserole, salsa chicken

Prep Time 5 minutes

Cook Time 30 minutes

Total Time 35 minutes

Servings 4

Calories 335kcal

Author Gwynn Galvin

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Ingredients

• 1 1/4 lbs. boneless skinless chicken breasts
• 2 Tbs. homemade taco seasoning or store bought taco seasoning
• 1 jar (16 oz.) salsa
• 1 1/2 cups shredded cheddar cheese
• 2 Tbs. chopped cilantro

Serving Suggestions:

• sour cream, sliced scallions and lime wedges

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Instructions

• Preheat oven to 375F.
• Coat a 2-quart baking dish with non-stick cooking spray.
• Season both sides of chicken with taco seasoning. Arrange in prepared baking dish. Top with salsa.
• Bake 25 minutes.
• Top with shredded cheese. Bake until chicken is cooked through and cheese is melted, 5 minutes. Meat thermometer should read 165F.
• Sprinkle with chopped cilantro. Serve with Fiesta Saffron Rice or hot cooked rice, if desired.

Serving suggestions:

• Serve your Salsa Chicken with sour cream, sliced scallions and lime wedges, if desired!

Video

Notes

Swirls of Flavor Recipe Tips

• Top with your favorite toppings, such as sour cream and scallions
• Serve with lime wedges
• Add some heat and top with pickled jalapenos
• Make with boneless skinless chicken thighs

Nutrition

Calories: 335kcal | Carbohydrates: 1g | Protein: 41g | Fat: 18g | Saturated Fat: 10g | Cholesterol: 135mg | Sodium: 530mg | Potassium: 566mg | Fiber: 1g | Sugar: 1g | Vitamin A: 598IU | Vitamin C: 2mg | Calcium: 313mg | Iron: 1mg

First Published: January 20, 2014... Last Updated: December 6, 2022 for better readability and user experience